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1

Effect of Melatonin on the Renin-Angiotensin-Aldosterone System in l-NAME-Induced Hypertension

Simko, Fedor, Baka, Tomas, Krajcirovicova, Kristina, Repova, Kristina, Aziriova, Silvia, Zorad, Stefan, Poglitsch, Marko, Adamcova, Michaela, Reiter, Russel, Paulis, Ludovit

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 3.11 MB

english, 2018

2

What prevents cardioprotective drugs from reaching the market?

Simko, Fedor, Adamcova, Michaela

Journal:

Expert Review of Clinical Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 398 KB

english, 2018

3

Iron chelation-afforded cardioprotection against chronic anthracycline cardiotoxicity: A study of salicylaldehyde isonicotinoyl hydrazone (SIH)

Martin Štěrba, Olga Popelová, Tomáš Šimůnek, Yvona Mazurová, Anna Potáčová, Michaela Adamcová, Ivana Gunčová, Helena Kaiserová, Vladimír Palička, Přemysl Poňka, Vladimír Geršl

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2007

4

Cardiac troponin T as an indicator of reduced left ventricular contractility in experimental anthracycline-induced cardiomyopathy

Tomáš Šimůnek, Ivona Klimtová, Michaela Adamcová, Vladimír Geršl, Radomír Hrdina, Martin Štěrba, Jana Kaplanová, Yvona Mazurová

Journal:

Cancer Chemotherapy and Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 224 KB

english, 2003

5

Cardiac troponin T in pregnant women having intravenous tocolytic therapy

Michaela Adamcová, Z. Kokštein, V. Palička, J. Vávrová, M. Košťál, M. Podholová, P. Kalous

Journal:

Archives of Gynecology and Obstetrics

Année:

1999

Langue:

english

Fichier:

PDF, 26 KB

english, 1999

6

Cardiac troponin T as a marker of myocardial damage caused by antineoplastic drugs in rabbits

Michaela Adamcová, Vladimír Geršl, Radomír Hrdina, Milan Mělka, Yvona Mazurová, Jaroslava Vávrová, Vladimír Palička, Zdeněk Kokštein

Journal:

Journal of Cancer Research and Clinical Oncology

Année:

1999

Langue:

english

Fichier:

PDF, 121 KB

english, 1999

7

Myocardial content of selected elements in experimental anthracycline-induced cardiomyopathy in rabbits

Tomáš Šimůnek, Martin Štěrba, Magdaléna Holečková, Jana Kaplanová, Ivona Klimtová, Michaela Adamcová, Vladimír Geršl, Radomír Hrdina

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 214 KB

english, 2005

8

In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity

Michaela Adamcová, Tomáš Šimůnek, Helena Kaiserová, Olga Popelová, Martin Štěrba, Anna Potáčová, Jaroslava Vávrová, Jana Maláková, Vladimír Geršl

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 543 KB

english, 2007

9

Veterinary and toxicological applications for the detection of cardiac injury using cardiac troponin

Mariana Serra, Stratos Papakonstantinou, Michaela Adamcova, Peter James O’Brien

Journal:

The Veterinary Journal

Année:

2010

Langue:

english

Fichier:

PDF, 456 KB

english, 2010

10

Cardiac remodeling and the role of matrix metalloproteinases in chronic anthracycline cardiotoxicity

Anna Potáèová, Michaela Adamcová, Martin Štìrba, Olga Popelová, Tomáš Šimùnek, Yvona Mazurová, Vladimír Geršl

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2006

Langue:

english

Fichier:

PDF, 59 KB

english, 2006

11

Proteomic insights into chronic anthracycline cardiotoxicity

Martin Štěrba, Olga Popelová, Juraj Lenčo, Alena Fučíková, Eva Brčáková, Yvona Mazurová, Eduard Jirkovský, Tomáš Šimůnek, Michaela Adamcová, Stanislav Mičuda, Jiří Stulík, Vladimír Geršl

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2011

Langue:

english

Fichier:

PDF, 2.63 MB

english, 2011

12

Regulatory proteins in cardiac muscle of children with congenital heart diseases

Michaela Adamcová, Jiři Kukačka, Václav Pelouch

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2001

Langue:

english

Fichier:

PDF, 136 KB

english, 2001

13

Troponins for predicting cardiotoxic or cardioprotective effects of new drugs

Michaela Adamcová, Vladimír Geršl, Jarmila Macháčková, Radomir Hrdina, Ivona Klimtová, Tomáš Šimůnek

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2002

Langue:

english

Fichier:

PDF, 140 KB

english, 2002

14

Proteomic analysis of the chronic anthracycline cardiotoxicity in rabbits

Martin Sterba, Juraj Lenco, Olga Popelova, Alena Fucikova, Tomas Simunek, Yvona Mazurova, Michaela Adamcova, Vladimir Gersl

Journal:

Toxicology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 103 KB

english, 2008

15

Comparison of protection by salicylaldehyde isonicotinoyl hydrazone (SIH) against hydrogen peroxide- and anthracycline-induced toxicity to cardiac cells

Tomas Simunek, Martin Sterba, Olga Popelova, Helena Kaiserova, Michaela Adamcova, Milos Hroch, Pavlina Haskova, Prem Ponka, Vladimir Gersl

Journal:

Toxicology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 97 KB

english, 2008

16

Comparison of protective effects of two iron chelating compounds – deferiprone and dexrazoxane – against chronic anthracycline cardiotoxicity

Olga Popelova, Martin Sterba, Tomas Simunek, Ivana Guncova, Yvona Mazurová, Milos Hroch, Michaela Adamcova, Vladimir Gersl

Journal:

Toxicology Letters

Année:

2008

Langue:

english

Fichier:

PDF, 73 KB

english, 2008

17

Steroid profiling in pregnancy: A focus on the human fetus

Hill, Martin, Pašková, Andrea, Kančeva, Radmila, Velíková, Marta, Kubátová, Jana, Kancheva, Lyudmila, Adamcová, Karolína, Mikešová, Michaela, Žižka, Zdeněk, Koucký, Michal, Šarapatková, Hana, Kačer, V

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Année:

2014

Langue:

english

Fichier:

PDF, 1.86 MB

english, 2014

18

Early and delayed cardioprotective intervention with dexrazoxane each show different potential for prevention of chronic anthracycline cardiotoxicity in rabbits

Jirkovský, Eduard, Lenčová-Popelová, Olga, Hroch, Miloš, Adamcová, Michaela, Mazurová, Yvona, Vávrová, Jaroslava, Mičuda, Stanislav, Šimůnek, Tomáš, Geršl, Vladimír, Štěrba, Martin

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 4.50 MB

english, 2013

19

Anthracycline-induced cardiotoxicity: Overview of studies examining the roles of oxidative stress and free cellular iron

Šimůnek, Tomáš, Štěrba, Martin, Popelová, Olga, Adamcová, Michaela, Hrdina, Radomír, Geršl, Vladimír

Journal:

Pharmacological Reports

Année:

2009

Langue:

english

Fichier:

PDF, 358 KB

english, 2009

20

Melatonin reduces cardiac remodeling and improves survival in rats with isoproterenol-induced heart failure

Simko, Fedor, Bednarova, Kristina Repova, Krajcirovicova, Kristina, Hrenak, Jaroslav, Celec, Peter, Kamodyova, Natalia, Gajdosechova, Lucia, Zorad, Stefan, Adamcova, Michaela

Journal:

Journal of Pineal Research

Année:

2014

Langue:

english

Fichier:

PDF, 353 KB

english, 2014

21

Pyridoxal Isonicotinoyl Hydrazone (PIH) and its Analogs as Protectants Against Anthracycline-Induced Cardiotoxicity*

Simunek, Tomas, Sterba, Martin, Popelova, Olga, Kaiserova, Helena, Potacova, Anna, Adamcova, Michaela, Mazurova, Yvona, Ponka, Premysl, Gersl, Vladimir

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 221 KB

english, 2008

22

Comparative study of chronic toxic effects of daunorubicin and doxorubicin in rabbits

Klimtová, Ivona, Šimunek, Tomáš, Mazurová, Yvona, Hrdina, Radomír, Geršl, Vladimír, Adamcová, Michaela

Journal:

Human & Experimental Toxicology

Année:

2002

Langue:

english

Fichier:

PDF, 481 KB

english, 2002

23

Effects of captopril, spironolactone, and simvastatin on the cardiovascular system of non-diseased Wistar rats

Simko, Fedor, Pechanova, Olga, Krajcirovicova, Kristina, Matuskova, Jana, Pelouch, Vaclav, Adamcova, Michaela, Paulis, Ludovit

Journal:

International Journal of Cardiology

Année:

2015

Langue:

english

Fichier:

PDF, 909 KB

english, 2015

24

Rabbit model for in vivo study of anthracycline-induced heart failure and for the evaluation of protective agents

Šimůnek, Tomáš, Klimtová, Ivona, Kaplanová, Jana, Mazurová, Yvona, Adamcová, Michaela, Štěrba, Martin, Hrdina, Radomír, Geršl, Vladimír

Journal:

European Journal of Heart Failure

Année:

2004

Langue:

english

Fichier:

PDF, 833 KB

english, 2004

25

Fetal complications due to intrahepatic cholestasis of pregnancy

Šimják, Patrik, Pařízek, Antonín, Vítek, Libor, Černý, Andrej, Adamcová, Karolína, Koucký, Michal, Hill, Martin, Dušková, Michaela, Stárka, L’uboslav

Journal:

Journal of Perinatal Medicine

Année:

2015

Langue:

english

Fichier:

PDF, 942 KB

english, 2015

26

Hypertension and Cardiovascular Remodelling in Rats Exposed to Continuous Light: Protection by ACE-Inhibition and Melatonin

Simko, Fedor, Pechanova, Olga, Repova Bednarova, Kristina, Krajcirovicova, Kristina, Celec, Peter, Kamodyova, Natalia, Zorad, Stefan, Kucharska, Jarmila, Gvozdjakova, Anna, Adamcova, Michaela, Paulis,

Journal:

Mediators of Inflammation

Année:

2014

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2014

27

Myocardial regulatory proteins and heart failure

Adamcová, Michaela, Štěrba, Martin, Šimůnek, Tomáš, Potáčová, Anna, Popelová, Olga, Geršl, Vladimír

Journal:

European Journal of Heart Failure

Année:

2006

Langue:

english

Fichier:

PDF, 175 KB

english, 2006

28

Troponin as a marker of myocardiac damage in drug-induced cardiotoxicity

Adamcová, Michaela, Šterba, Martin, Šimunek, Tomáš, Potácová, Anna, Popelová, Olga, Mazurová, Yvona, Geršl, Vladimír

Journal:

Expert Opinion on Drug Safety

Année:

2005

Langue:

english

Fichier:

PDF, 182 KB

english, 2005

29

Experimental determination of diagnostic window of cardiac troponins in the development of chronic anthracycline cardiotoxicity and estimation of its predictive value

Adamcova, Michaela, Lencova-Popelova, Olga, Jirkovsky, Eduard, Mazurova, Yvona, Palicka, Vladimir, Simko, Fedor, Gersl, Vladimir, Sterba, Martin

Journal:

International Journal of Cardiology

Année:

2015

Langue:

english

Fichier:

PDF, 1.77 MB

english, 2015

30

Cardioprotective effects of inorganic nitrate/nitrite in chronic anthracycline cardiotoxicity: Comparison with dexrazoxane

Lenčová-Popelová, Olga, Jirkovský, Eduard, Jansová, Hana, Jirkovská-Vávrová, Anna, Vostatková-Tichotová, Lucie, Mazurová, Yvona, Adamcová, Michaela, Chládek, Jaroslav, Hroch, Miloš, Pokorná, Zuzana, G

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2016

Langue:

english

Fichier:

PDF, 2.52 MB

english, 2016

31

Melatonin improves the restoration of endothelium-derived constricting factor signalling and inner diameter in the rat femoral artery after cessation of L-NAME treatment

Paulis, Ludovit, Pechanova, Olga, Zicha, Josef, Liskova, Silvia, Celec, Peter, Mullerova, Martina, Kollar, Jakub, Behuliak, Michal, Kunes, Jaroslav, Adamcova, Michaela, Simko, Fedor

Journal:

Journal of Hypertension

Année:

2010

Langue:

english

Fichier:

PDF, 316 KB

english, 2010

32

Effect of melatonin, captopril, spironolactone and simvastatin on blood pressure and left ventricular remodelling in spontaneously hypertensive rats

Simko, Fedor, Pechanova, Olga, Pelouch, Vaclav, Krajcirovicova, Kristina, Mullerova, Martina, Bednarova, Kristina, Adamcova, Michaela, Paulis, Ludovit

Journal:

Journal of Hypertension

Année:

2009

Langue:

english

Fichier:

PDF, 252 KB

english, 2009

33

Melatonin prevents fibrosis but not hypertrophy development in the left ventricle of NG-nitro-L-arginine-methyl ester hypertensive rats

Paulis, Ludovit, Pechanova, Olga, Zicha, Josef, Krajcirovicova, Kristina, Barta, Andrej, Pelouch, Vaclav, Adamcova, Michaela, Simko, Fedor

Journal:

Journal of Hypertension

Année:

2009

Langue:

english

Fichier:

PDF, 347 KB

english, 2009

34

Continuous light and L-NAME-induced left ventricular remodelling: different protection with melatonin and captopril

Simko, Fedor, Pechanova, Olga, Pelouch, Vaclav, Krajcirovicova, Kristina, Celec, Peter, Palffy, Roland, Bednarova, Kristina, Vrankova, Stanislava, Adamcova, Michaela, Paulis, Ludovit

Journal:

Journal of Hypertension

Année:

2010

Langue:

english

Fichier:

PDF, 261 KB

english, 2010

35

Are cardioprotective effects of NO-releasing drug molsidomine translatable to chronic anthracycline cardiotoxicity settings?

Lenčová-Popelová, Olga, Jansová, Hana, Jirkovský, Eduard, Bureš, Jan, Jirkovská-Vávrová, Anna, Mazurová, Yvona, Reimerová, Petra, Vostatková, Lucie, Adamcová, Michaela, Hroch, Miloš, Pokorná, Zuzana,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.54 MB

english, 2016

36

Exposure to bisphenols and parabens during pregnancy and relations to steroid changes

Kolatorova, Lucie, Vitku, Jana, Hampl, Richard, Adamcova, Karolina, Skodova, Tereza, Simkova, Marketa, Parizek, Antonin, Starka, Luboslav, Duskova, Michaela

Journal:

Environmental Research

Année:

2018

Langue:

english

Fichier:

PDF, 259 KB

english, 2018

37

Multiplex biomarker approach to cardiovascular diseases

Adamcova, Michaela, Šimko, Fedor

Journal:

Acta Pharmacologica Sinica

Année:

2018

Langue:

english

Fichier:

PDF, 384 KB

english, 2018

38

A Comprehensive Evaluation of Steroid Metabolism in Women with Intrahepatic Cholestasis of Pregnancy

Pařízek, Antonín, Hill, Martin, Dušková, Michaela, Vítek, Libor, Velíková, Marta, Kancheva, Radmila, Šimják, Patrik, Koucký, Michal, Kokrdová, Zuzana, Adamcová, Karolína, Černý, Andrej, Hájek, Zdeněk,

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 2.49 MB

english, 2016

39

Lactacystin-Induced Model of Hypertension in Rats: Effects of Melatonin and Captopril

Simko, Fedor, Pechanova, Olga, Repova, Kristina, Aziriova, Silvia, Krajcirovicova, Kristina, Celec, Peter, Tothova, Lubomira, Vrankova, Stanislava, Balazova, Lucia, Zorad, Stefan, Adamcova, Michaela

Journal:

International Journal of Molecular Sciences

Année:

2017

Langue:

english

Fichier:

PDF, 2.39 MB

english, 2017

40

Effect of Ivabradine on a Hypertensive Heart and the Renin-Angiotensin-Aldosterone System in L-NAME-Induced Hypertension

Simko, Fedor, Baka, Tomas, Poglitsch, Marko, Repova, Kristina, Aziriova, Silvia, Krajcirovicova, Kristina, Zorad, Stefan, Adamcova, Michaela, Paulis, Ludovit

Journal:

International Journal of Molecular Sciences

Année:

2018

Langue:

english

Fichier:

PDF, 3.21 MB

english, 2018

41

Assessment of phytotoxicity, environmental and health risks of historical urban park soils

Brtnický, Martin, Pecina, Václav, Hladký, Jan, Radziemska, Maja, Koudelková, Zuzana, Klimánek, Martin, Richtera, Lukáš, Adamcová, Dana, Elbl, Jakub, Galiová, Michaela Vašinová, Baláková, Ludmila, Kyni

Journal:

Année:

2019

Langue:

english

Fichier:

PDF, 2.01 MB

english, 2019

42

Cardiac Troponins are Among Targets of Doxorubicin-Induced Cardiotoxicity in hiPCS-CMs

Adamcova, Michaela, Skarkova, Veronika, Seifertova, Jitka, Rudolf, Emil

Journal:

International Journal of Molecular Sciences

Année:

2019

Langue:

english

Fichier:

PDF, 2.66 MB

english, 2019

43

Cardiac Troponins are Among Targets of Doxorubicin-Induced Cardiotoxicity in hiPCS-CMs

Adamcova, Michaela, Skarkova, Veronika, Seifertova, Jitka, Rudolf, Emil

Journal:

International Journal of Molecular Sciences

Année:

2019

Fichier:

PDF, 2.66 MB

2019

44

Antiarrhythmic Effects of Melatonin and Omega-3 Are Linked with Protection of Myocardial Cx43 Topology and Suppression of Fibrosis in Catecholamine Stressed Normotensive and Hypertensive Rats

Szeiffova Bacova, Barbara, Viczenczova, Csilla, Andelova, Katarina, Sykora, Matus, Chaudagar, Kiranj, Barancik, Miroslav, Adamcova, Michaela, Knezl, Vladimir, Egan Benova, Tamara, Weismann, Peter, Sle

Journal:

Année:

2020

Fichier:

PDF, 11.89 MB

2020

45

Ivabradine Ameliorates Kidney Fibrosis in L-NAME-Induced Hypertension

Stanko, Peter, Baka, Tomas, Repova, Kristina, Aziriova, Silvia, Krajcirovicova, Kristina, Barta, Andrej, Janega, Pavol, Adamcova, Michaela, Paulis, Ludovit, Simko, Fedor

Journal:

Frontiers in Medicine

Année:

2020

Fichier:

PDF, 8.00 MB

2020

46

Ivabradine Improves Survival and Attenuates Cardiac Remodelling in IsoproterenolâInduced Myocardial Injury

Simko, Fedor, Baka, Tomas, Repova, Kristina, Aziriova, Silvia, Krajcirovicova, Kristina, Paulis, Ludovit, Adamcova, Michaela

Journal:

Fundamental & Clinical Pharmacology

Année:

2020

Fichier:

PDF, 34.99 MB

2020

47

[BMJ Publishing Group Ltd and British Cardiovascular Society British Cardiovascular Society Annual Conference âDigital Health Revolutionâ 3â5 June 2019 - ()] Heart Failure - 79âEffective cardioprotection against anthracycline cardiotoxicity in isolated cardiomyocytes and rabbits is based on dexrazoxane interaction with topoisomerase II beta instead of iron chelation by its metabolite ADR-925

Jirkovsky, Eduard, Jirkovska, Anna, Bavlovic-Piskackova, Hana, Skalicka, Veronika, Pokorna, Zuzana, Karabanovich, Galina, Brazdova, Petra, Lencova-Popelova, Olga, Mazurova, Yvona, Adamcova, Michaela,

Année:

2019

Fichier:

PDF, 52 KB

2019